Discover how childhood trauma affects the brain, body, and emotional health—and why it doesn’t have to define your future. Read on to learn about ACE scores, how trauma shows up in everyday life, and how innovative treatments like EMDR and microdose ketamine are helping people heal and move forward.

Joyous Team
5min
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Unpacking Childhood Trauma

Childhood is meant to be a time of safety, curiosity, and growth. But for many, it's marked by adverse experiences that leave lasting imprints well into adulthood. These early events can shape how we think, feel, and move through the world—often in ways we may not fully recognize until years later. The good news? Healing is possible, and it's increasingly supported by innovative, evidence-based therapies. First, we’ll take a closer look at how trauma shows up in our lives—then explore some of the promising treatments that are helping people heal.

Trauma Lives in the Body and Mind

Trauma doesn’t just live in our memories—it reshapes our nervous systems. The autonomic nervous system, which is responsible for maintaining internal balance by monitoring our inner and outer environments, shifts into survival mode when it perceives danger. This response can manifest as anxiety, irritability, muscle tension, digestive issues, or emotional numbness. Over time, ongoing physiological stress can push the system from a state of regulation into dysregulation, wiring us to expect danger, distrust safety, and anticipate abandonment. Even in calm moments, these patterns can persist, affecting our relationships, self-esteem, physical health, and daily functioning.

Science confirms that trauma isn’t just psychological—it impacts the brain, immune system, and even gene expression. Studies show changes in key brain areas like the amygdala (fear responses), hippocampus (memory), and prefrontal cortex (emotional regulation and decision-making). Chronic trauma can also disrupt the hypothalamic-pituitary-adrenal (HPA) axis, leading to a heightened and prolonged stress response throughout life.

It’s also important to recognize that trauma can look very different from one person to another. While some experiences like physical abuse are more overt, others—such as emotional neglect, chronic criticism, or inconsistent caregiving—can be just as damaging. What matters is not only what happened, but how it was experienced by the individual and whether they had the support needed to process it.

To better understand the long-term effects of these early experiences, researchers developed a tool to measure them—known as the ACE scores. 

A Measure of Childhood Adversity  

ACE, or Adverse Childhood Experiences, is a term coined from a landmark CDC-Kaiser Permanente study that examined the relationship between childhood trauma and long-term health outcomes. ACEs include experiences such as physical or emotional abuse, neglect, witnessing domestic violence, or growing up with a family member who struggles with mental illness or substance abuse.

Each 'yes' to the ten ACE questions counts as one point, and higher scores are strongly correlated with increased risks of depression, anxiety, chronic illness, and even early death. For example, someone with an ACE score of 4 or more is significantly more likely to experience serious mental and physical health challenges later in life. 

But the ACE score isn’t destiny. It’s a map—a tool that helps us understand the terrain of our emotional lives and offers direction toward healing.

That’s where modalities like EMDR (Eye Movement Desensitization and Reprocessing) and treatments such as low-dose ketamine treatment come into play.

EMDR: Reprocessing to Release

EMDR is a psychotherapy technique developed to help people reprocess traumatic memories. It uses bilateral stimulation—such as guided eye movements or tapping—to reduce the emotional charge of painful memories and shift the way they are stored in the brain. EMDR has been recognized by organizations like the WHO and the APA as an effective treatment for PTSD and other trauma-related disorders.

In essence, EMDR allows the brain to rewire itself, helping clients move from a place of reactivity and fear to one of integration and healing.

Low-dose Ketamine: A New Frontier in Trauma Healing

Ketamine, originally developed as an anesthetic, has gained recognition in recent years for its rapid-acting antidepressant effects. In microdoses—far below the levels used in full psychedelic treatments—ketamine supports neuroplasticity, the brain's ability to create new neural connections.

Joyous microdose ketamine treatment is a promising new approach for those working with trauma. Unlike traditional pharmaceuticals, which often aim to suppress symptoms, ketamine in microdoses can enhance openness, support emotional regulation, and create a mental state conducive to therapeutic breakthroughs. It often pairs beautifully with therapies like EMDR, creating a "window of tolerance" where clients feel safe enough to access and process difficult memories.

The Hope of Integration

Healing from childhood trauma doesn’t mean forgetting the past or pretending it didn’t matter. It means learning to understand how those early experiences have shaped us, and gradually building the tools and support we need to move forward. Resources like ACE scores can help us identify the impact, while approaches like EMDR and microdose ketamine treatment offer new ways to work through the pain and reconnect with ourselves.

While healing looks different for everyone, it is possible. With the right combination of therapies, relationships, and inner work, people can move from surviving to thriving—not defined by what happened to them, but empowered by the growth that follows.

Meet Joyous

Joyous is an effective, accessible, at-home mental health treatment that utilizes very low doses of ketamine paired with curated treatment courses to help patients overcome depression, anxiety, PTSD, and more.
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