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Low-dose Ketamine treatment is a breakthrough, effective, and accessible option for millions of people struggling with depression and anxiety.
We've treated over 50,000 patients with extraordinary results, including for patients with treatment-resistant depression.
Ketamine is believed to affect neuroplasticity and mood regulation through its modulation of glutamate and its interactions with NMDA receptors. By blocking NMDA receptors, ketamine disrupts normal glutamate neurotransmission, supporting synaptic plasticity and contributing to the antidepressant effects found with ketamine treatment. Patients are able to make new neural connections and gain new perspectives over old triggers, beliefs, and experiences.
Ketamine is also believed to stimulate synaptogenesis by increasing BDNF (brain-derived neurotrophic factor) levels in certain brain regions. Depression and chronic stress can cause synaptic dysfunction by reducing the number of neuronal synapses in brain regions that regulate mood and cognition. Ketamine has been shown to promote the growth of new synapses, called synaptogenesis, contributing to the long-term antidepressant potential of ketamine treatment.
There is no set timeline, you can participate in our low-dose ketamine treatment long term if you feel it is benefitting you, or you can come off it at any time. Many of our patients have been on the Joyous treatment for years and still have mental health benefits, while others stop when they feel that is right for them.
When/if you decide to come off of the medication, withdrawal symptoms are rare in a clinical setting, and we will provide you with our medical recommendations to ensure that you do not have a bad experience ending treatment. The length of treatment is personal to every patient, and you have complete say over how long you take ketamine.
Withdrawal symptoms are rare in our clinical setting, and our team creates a plan to help patients stop treatment safely when they feel they are ready. As time passes and the ketamine is out of your system, the neuroplasticity benefits may begin to dull, but can be reactivated by starting treatment again.
Good candidates for the Joyous treatment are people who have tried therapy and/or traditional medications in the past and didn't feel like that was enough or the right kind of treatment for them. People who suffer from depression and anxiety commonly experience relief from our treatment even when other protocols failed.
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