Learn about the experience of low-dose ketamine treatment, described by Joyous patients as a mental "reset" that alleviates stress, anxiety, and depression. This gentle yet powerful therapy promotes relaxation, emotional openness, and mental clarity without inducing full dissociation.

Joyous Team
3-5min
Get Started with Joyous

What Low-Dose Ketamine Treatment Feels Like

Starting a new treatment of any kind might feel a bit scary or overwhelming, and it is completely understandable to have some questions about what the experience is like. So, what does low-dose ketamine treatment actually feel like?

The Onset: A Gentle Shift

Unlike higher dose treatments, psycholytic doses of ketamine are carefully controlled to provide relief without inducing a full dissociative or psychedelic experience. The effects begin within 10-20 minutes, often with a sense of lightness, calm, or mild detachment from stressors. Many Joyous patients describe an initial wave of relaxation and clarity, as though a mental weight has been lifted. "I found it to be pleasant, peaceful, and supportive," says Brett A., a Joyous patient. Unlike higher doses, the shift in perception is subtle—thoughts may flow more freely, and worries may seem less pressing. Some people say they feel as if they are entering a meditative state, yet they remain fully grounded in reality.

The Experience: A Heightened Sense of Awareness 

During the session, which typically lasts 30–60 minutes, patients often describe a sense of introspection and emotional openness. The mind becomes more malleable (receptive to therapeutic practices, mindfulness, and feeling present), allowing suppressed emotions and thoughts to surface without overwhelming distress. 

This makes it particularly useful for therapy sessions, as it enables individuals to process difficult emotions with greater ease, even challenging triggers that are otherwise too uncomfortable to access. One therapist shared her experience observing a patient using Joyous Low Dose Ketamine Treatment, stating, “I noticed that their window of tolerance expands. So we're still able to work fully conscious, fully aware, but there is almost like a blanket of support or ease that's present when the ketamine is online” - Miya Guten, LCSW

The Aftermath: A Lift in Mood and Clarity

As the full effects of ketamine treatment wear off, which happens within an hour or two, most people report feeling emotionally balanced and even optimistic. Some describe it as a “reset” for their brain, as though intrusive thoughts, stress, and anxiety have been dialed down significantly. 

“It gives you a greater sense of self-power, self-love and self-realization” - Brandi S., Joyous Patient

Unlike traditional antidepressants that reportedly take weeks to show effects, the antidepressant and antianxiety benefits of ketamine treatment can often be felt within hours or days after starting treatment. Of course, all bodies are different and while most patients report significant improvements in their first few weeks of Joyous mental health treatment, other patients experience the most impactful improvements in months 2 and 3. More importantly, low-dose ketamine treatment is not about escaping reality or numbing emotions like other treatments do, but it’s a powerful tool that empowers you to process underlying emotions, reconnect with your joyful self, and build new neural pathways that allow you to handle life’s ups and downs with more resilience. The experience is well-tolerated, with minimal side effects beyond mild fatigue. It is important to note that no one experience is the same, and it will vary based on individual and dose strength.. 

For those seeking relief from depression, anxiety, PTSD, or chronic stress, Joyous low-dose ketamine treatment serves as a new avenue for mental health healing. With our curated medical guidance, personalized doses, and therapeutic resources, it provides a unique opportunity to rewire our thought patterns and establish a new relationship with the self.

Meet Joyous

Joyous is an effective, accessible, at-home mental health treatment that utilizes very low doses of ketamine paired with curated treatment courses to help patients overcome depression, anxiety, PTSD, and more.
  • Safely monitored by medical providers
  • Personalized treatment and daily check-ins
  • $129/mo, including medication, provider appointments, and at-home therapy practices
Get Started
Photo of a man having a telehealth consultation with Joyous licensed medical provider

See also